Tag: Genomics
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Genomic study reveals epigenetic drivers in osteosarcoma guiding tailored therapies
New genomic insights illuminate osteosarcoma biology Osteosarcoma, the most common bone cancer in children and adolescents, has long challenged clinicians with its aggressive course and tendency toward chemotherapy resistance. A new study led by Livia Garzia, PhD, Nada Jabado, MD, PhD, and Claudia Kleinman, PhD, from The Research Institute of the McGill University Health Centre…
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Genomic Insights Offer Hope for Tailored Osteosarcoma Therapies
New genomic study highlights epigenetic drivers of osteosarcoma An international team led by Livia Garzia, PhD, Nada Jabado, MD, PhD, and Claudia Kleinman, PhD, has unveiled important epigenetic features in osteosarcoma, offering fresh directions for prognosis and treatment. The findings, published in Nature Communications, illuminate how epigenetic regulation shapes this aggressive bone cancer that primarily…
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Mitochondrial Genome of Plasmodium pitheci in Bornean Orang-utans Reveals Close Relations Within Orang-utan Malaria Lineages
Background: Orang-utan malaria and the Plasmodium pitheci discovery Malaria in non-human primates (NHP) spans a diverse genus, with Plasmodium species infecting a broad host range. Among Asian NHPs, orang-utans (Pongo spp.) harbor Plasmodium pitheci and Plasmodium sylvaticum, parasites historically identified by morphology but lacking validated molecular characterization until now. The present work focuses on the…
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How Bats Reused Old Genes to Take Flight: The Evolution of the Wing
Introduction: The Mystery Behind a Flying Mammal Bats are the only mammals capable of true powered flight. Their wings differ dramatically from the typical mammalian limb, yet they sprouted from the same five-digit limb pattern found in mice, humans, and dolphins. How did evolution turn a familiar blueprint into a remarkable flying apparatus? Early expectations…
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Explainable AI in Cancer Detection: Dr. Sakib Mostafa’s Path from Fear to Innovation
Unpacking the Black Box: Why Explainable AI Matters Artificial intelligence is reshaping healthcare, but its most consequential risks aren’t tubes of metal marching toward dystopian futures. They’re systems whose decisions are opaque, creating trust gaps when lives are on the line. Dr. Sakib Mostafa’s work centers on explainable AI—the science of making AI decisions understandable…
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Scientists Discover Hidden Gecko Species In Atacama Desert
Unveiling the Hidden Diversity of Atacama Geckos Beneath the sun-scorched skies of Chile’s Atacama Desert, a tiny reptile is reshaping our understanding of biodiversity. Using cutting-edge genomic tools, a team led by Kamryn Carter of the University of Wollongong (UOW) has revealed that the Garthia geckos, also known as Chilean marked geckos, comprise far more…
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Garthia Geckos: Hidden Species Discovered in the Atacama Desert
Uncovering Hidden Biodiversity in one of the World’s Harshest Frontiers In Chile’s Atacama Desert, famed as the driest place on Earth, a tiny group of geckos is rewriting what scientists thought they knew about species diversity. A cutting-edge genomic study led by researchers including Kamryn Carter from the University of Wollongong (UOW) reveals that the…
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Hidden Gecko Diversity: Genomics Reveal 11 Species in Chile’s Atacama Desert
Unveiling a Hidden World in the Atacama In the world’s driest desert, a tiny reptile is rewriting a long-standing biodiversity puzzle. Scientists using cutting-edge genomic tools have revealed that the Garthia geckos, also known as Chilean marked geckos, are far more diverse than previously thought. What appeared to be a single, uniform species across the…
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HIV Hides in Body DNA by Tissue Type – Canadian Study
Overview: A tissue-specific look at HIV persistence Researchers from Western University and the University of Calgary have uncovered a new layer of detail about how HIV persists in the human body. Their work shows that the virus does not integrate randomly into the genome. Instead, HIV embeds itself into cell DNA in patterns that vary…
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HIV Hides in Tissue-Specific DNA: Canadian Study Maps Viral Reservoirs
Overview: Why the search for HIV reservoirs matters Researchers across Canada have taken a significant step toward understanding why HIV persists despite decades of antiretroviral therapy. A collaborative study led by Stephen Barr at Western University and Guido van Marle at the University of Calgary reveals that HIV does not integrate randomly into the human…