Tag: Genomics
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QIMR Berghofer Bill 2025 Passes Parliament: A New Era for Queensland Medical Research
Overview: A landmark moment for QIMR Berghofer The Queensland Institute of Medical Research (QIMR) Bill 2025 has officially passed Parliament, marking a turning point for QIMR Berghofer as it enters a new era of governance, transparency, and agility. Originating as a 1945 Act, the legislative reform repeals the old framework and introduces a contemporary structure…
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From ‘superhumans’ to sequencing: How the next 50 years of science could shape our world
Imagining the next half-century of science The last 50 years have reshaped our world with breakthroughs once thought impossible—from the birth of the internet to decoding the human genome and the rapid rise of artificial intelligence. As CBC Radio’s science program Quirks & Quarks marks its 50th anniversary, a panel of Canada’s leading researchers gathered…
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From ‘Superhumans’ to Sequencing: What the Next 50 Years of Science Could Bring
Introduction: A World Transformed, With More Change Ahead The last five decades have rewritten what’s possible in science. From the birth of the internet to the decoding of the human genome and the rapid rise of artificial intelligence, our worldview has expanded in ways once deemed science fiction. As we mark the 50th anniversary of…
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Depression Brain Cells Identified: Key Neurons and Microglia
Groundbreaking study pinpoints brain-cell targets in depression In a landmark effort to understand the biology of depression, researchers have for the first time pinpointed the exact brain cell types where gene activity and DNA regulation are disrupted. The team combined advanced genomic techniques with post-mortem brain tissue to identify the cells most affected by depression,…
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Depression Revealed: Specific Brain Cells Linked to the Condition Identified by Researchers
New Breakthrough Maps Which Brain Cells Carry Depression For the first time, scientists have pinpointed the exact brain cell types that change in depression by combining gene activity maps with DNA regulatory mechanisms. The discovery comes from analyzing post-mortem brain tissue with cutting-edge, single-cell genomic methods, shedding new light on the biological roots of a…
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For the first time, scientists pinpoint brain cells linked to depression
Groundbreaking discovery maps which brain cells are affected in depression In a landmark study, researchers have for the first time pinpointed the specific brain cell types that show altered activity in depression. By combining gene activity data with mechanisms that regulate the DNA code, the team has created a clearer map of where disruptions occur…
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Pan-Cancer AI Model Elevates Prognosis Across 30 Cancer Types with MICE
Transforming Pan-Cancer Prognosis with Multimodal AI In the rapidly evolving field of oncology, a novel multimodal AI model named MICE (Multimodal data Integration via Collaborative Experts) is breaking new ground in pan-cancer prognosis prediction. By integrating pathology images, genomics, and clinical data, MICE demonstrates superior generalizability and efficiency across 30 cancer types. The approach aims…
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Comparative Chloroplast Genomics of Erigeron (Asteroideae, Asteraceae): Insights from a Broad Phylogenomic Survey
Overview: Why Compare Erigeron Chloroplast Genomes? Erigeron, commonly known as fleabanes, includes hundreds of species spread across temperate and mountainous regions worldwide. Unraveling their evolutionary relationships is challenging due to polyphyly, hybridization, and taxonomic ambiguity, especially among Old World taxa. A comprehensive comparative study of chloroplast (cp) genomes provides a stable, maternally inherited genetic framework…
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Genomic study reveals epigenetic drivers in osteosarcoma guiding tailored therapies
New genomic insights illuminate osteosarcoma biology Osteosarcoma, the most common bone cancer in children and adolescents, has long challenged clinicians with its aggressive course and tendency toward chemotherapy resistance. A new study led by Livia Garzia, PhD, Nada Jabado, MD, PhD, and Claudia Kleinman, PhD, from The Research Institute of the McGill University Health Centre…
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Genomic Insights Offer Hope for Tailored Osteosarcoma Therapies
New genomic study highlights epigenetic drivers of osteosarcoma An international team led by Livia Garzia, PhD, Nada Jabado, MD, PhD, and Claudia Kleinman, PhD, has unveiled important epigenetic features in osteosarcoma, offering fresh directions for prognosis and treatment. The findings, published in Nature Communications, illuminate how epigenetic regulation shapes this aggressive bone cancer that primarily…