Tag: Genomics
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Identification of Novel TERT Promoter Mutations in Chronic Hepatitis B and Their Link to Hepatocellular Carcinoma
Background: Hepatitis B and Liver Cancer Risk Liver cancer remains a major global health challenge, with hepatocellular carcinoma (HCC) being the most common form. Chronic hepatitis B virus (HBV) infection is a well-established driver of HCC, contributing to carcinogenesis through chronic inflammation, liver injury, and genomic instability. In recent years, researchers have turned a spotlight…
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Identification of Novel TERT Promoter Mutations in Chronic Hepatitis B
Introduction Chronic Hepatitis B infection remains a major global health challenge, with a well-established link to hepatocellular carcinoma (HCC). Recent research has turned its attention to the telomerase reverse transcriptase (TERT) promoter, a genomic region that regulates telomerase activity and cellular immortality. While TERT promoter mutations have been documented in various cancers, their role in…
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Identification of Novel TERT Promoter Mutations in Chronic Hepatitis B and Hepatocellular Carcinoma Risk
Introduction Liver cancer remains a major global health challenge, with hepatocellular carcinoma (HCC) as its most common form. Chronic hepatitis B virus (HBV) infection is a leading driver of HCC, particularly in regions with high HBV prevalence. Recent research has focused on the genetic and molecular underpinnings of HBV-related liver cancer, including alterations in the…
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SOPHiA GENETICS Reports 2025 Results, Sets 2026 Guidance, and Announces CEO Transition
Strong Q4 2025 Performance and Full-Year Results SOPHiA GENETICS, a global leader in AI-driven precision medicine, announced preliminary fourth-quarter and full-year 2025 financial results, highlighting robust momentum as the company advances its AI-powered platform across life sciences and clinical applications. While the company noted that the 2025 results are preliminary, management emphasized solid quarterly execution…
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10x Genomics Announces Preliminary 2025 Q4 and Full-Year Results, Signals Continued Growth in Single-Cell and Spatial Biology
Overview of the Preliminary Results 10x Genomics, a leading player in the field of single-cell and spatial biology, released preliminary, unaudited select results for the fourth quarter and full year ended December 31, 2025. The company, listed on the Nasdaq under TXG, said the information is subject to adjustments as a result of year-end close…
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New Genetic Clues in Retinitis Pigmentosa Bring Hope for Future Treatments
Groundbreaking findings reveal five new genetic causes of retinitis pigmentosa In a major advance for eye health research, scientists analyzing data from Genomics England’s National Genomic Research Library (NGRL) and other sources have identified five new genetic causes of retinitis pigmentosa (RP). RP is a progressive eye condition that damages the retina’s light-sensing cells, often…
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Drone Imaging Strategy Enhances Crop Genetic Signals
Overview: A New Era for Crop Genomics Researchers are turning to drone imaging to refine how we measure plant performance in the field. By training statistical and machine-learning models to predict expert visual scores, the study demonstrates that phenomics—high-throughput, image-based phenotyping—can match or even outpace traditional indices used to gauge crop health and yield potential.…
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Stop and re-check everything: 26 new bacterial species found in NASA cleanrooms
Overview: A surprising find in NASA’s sterile environments NASA’s cleanrooms are not just pristine laboratories; they are carefully controlled environments designed to prevent microbial contamination from hitching a ride on spacecraft. In a recent and surprising discovery, researchers identified 26 previously unknown bacterial species living in these ultra-clean facilities. The finding challenges assumptions about how…
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3D Maps of the Human Genome: A Landmark Leap in Genomic Architecture
Groundbreaking 3D Maps Shed Light on Genome Architecture In a landmark collaboration, Northwestern University researchers and the 4D Nucleome Project have unveiled the most detailed three‑dimensional maps of the human genome to date. These maps chart how the genome’s physical structure—its looping, folding, and spatial neighborhood—shapes gene regulation, cell identity, and disease processes. By moving…
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Researchers unveil most detailed 3D maps of the human genome
Groundbreaking 3D maps illuminate the genome’s hidden architecture In a landmark achievement, researchers from Northwestern University and the 4D Nucleome Project have released the most detailed three-dimensional (3D) maps of the human genome to date. These maps chart how the long strands of DNA fold and interact inside the nucleus, offering new insights into how…