Tag: genome architecture


  • 3D Maps of the Human Genome: A Landmark Leap in Genomic Architecture

    3D Maps of the Human Genome: A Landmark Leap in Genomic Architecture

    Groundbreaking 3D Maps Shed Light on Genome Architecture In a landmark collaboration, Northwestern University researchers and the 4D Nucleome Project have unveiled the most detailed three‑dimensional maps of the human genome to date. These maps chart how the genome’s physical structure—its looping, folding, and spatial neighborhood—shapes gene regulation, cell identity, and disease processes. By moving…

  • Tiny genome loops persist through mitosis, reshaping our view of cell division

    Tiny genome loops persist through mitosis, reshaping our view of cell division

    New insight into mitosis: small loops endure where larger structures fall away In a surprising turn for how we understand cell division, MIT researchers have found that tiny 3D loops in the genome persist—or even strengthen—during mitosis, the process by which a cell copies its DNA and divides into two daughter cells. This discovery challenges…