Tag: gene regulation
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Researchers Reveal a Powerful New Gene-Switch Tool
Groundbreaking Gene-Switch Technology Emerges from Weill Cornell Medicine Researchers at Weill Cornell Medicine have unveiled a versatile, non-toxic technology designed to precisely control the activity of any gene within a cell. Dubbed a “gene-switch” tool, this system enables scientists to selectively turn a target gene on or off, providing a powerful platform for understanding gene…
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Researchers Unveil a Powerful New Gene-Switch Tool
A Breakthrough in Gene Regulation Researchers at Weill Cornell Medicine have introduced a versatile, non-toxic technology that can control the activity of any gene in a cell. Dubbed a “gene-switch” tool, this innovation promises to give scientists a reliable way to turn on or turn off a target gene, enabling deeper exploration of gene function,…
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Tiny genome loops persist through mitosis, reshaping our view of cell division
New insight into mitosis: small loops endure where larger structures fall away In a surprising turn for how we understand cell division, MIT researchers have found that tiny 3D loops in the genome persist—or even strengthen—during mitosis, the process by which a cell copies its DNA and divides into two daughter cells. This discovery challenges…
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Tiny genome loops persist in dividing cells, reshaping mitosis understanding
Overview: A surprise in the mitotic genome For decades, scientists believed that as cells prepare to divide, their chromosomes condense into a tightly packed, featureless slate. Once division finished, the genome would gradually reestablish its complex 3D structure to regulate which genes are active in each daughter cell. A groundbreaking study from MIT challenges this…
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Tiny Genome Loops Persist During Cell Division, MIT Finds
New insight into mitosis: genome structure isn’t erased For decades, scientists believed that as cells divide, the genome is stripped of its intricate 3D organization and that this structure gradually returns only after mitosis. A groundbreaking MIT study challenges that view by showing that tiny 3D loops, known as microcompartments, persist throughout cell division and…
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Identification and Characterization of OvANS as the Key Driver of Purple Flowering in Orychophragmus violaceus
Overview Anthocyanins are vital pigments responsible for the rich purple hues seen in many flowers. In Orychophragmus violaceus, a Brassicaceae species native to China and valued for its ornamental appeal, purple flowers contrasted with white mutants provide a natural system to study the genetic control of flower coloration. Here, researchers identify and characterize OvANS (anthocyanidin…
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Ancient Viral DNA as a Key to Our First Moments of Life
Uncovering a Hidden Architect of Early Life Fragments of ancient viral DNA may have played an outsized role in the earliest stages of human life. In a study that blends evolution, virology and developmental biology, researchers have shown that remnants of endogenous retroviruses in our genome—specifically a group called LTR5Hs—can act as regulatory switches essential…
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An Ancient Infection May Shape Our First Moments of Life
Ancient Viral Remnants as Architects of Early Life Fragments of DNA from viruses that invaded our distant ancestors may be more than leftovers from a prehistoric battle. New research suggests these endogenous viral elements, particularly a group called LTR5Hs, act as firestarters for human development during the earliest moments after fertilization. Stanford biologist Raquel Fueyo…