Tag: ER-positive
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Global Lobular Breast Cancer Awareness Day Highlights Need for Improved Detection and Treatment
Raising Awareness for a Less-Recognized Breast Cancer Subtype Last week, lobular breast cancer patients and their providers gathered at Fred Hutch Cancer Center for a two-hour program timed to Global Lobular Breast Cancer Awareness Day. The event highlighted patient stories, epidemiological findings, and the latest developments in screening and clinical trials for invasive lobular carcinoma…
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LncRNAs and MAPK Signaling in Breast Cancer: Interplay Driving Pathogenesis and Therapy Options
Introduction: The MAPK Landscape in Breast Cancer MAPK signaling is a cornerstone of cellular decision-making, translating external cues into outcomes such as proliferation, differentiation, migration, and survival. In breast cancer, three major MAPK branches—ERK, JNK, and p38—coordinate responses to growth factors, cytokines, and stress signals. While mutations in upstream components frequently hijack this network, noncoding…
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Bray mum-of-five celebrates all-clear after bilateral breast cancer battle
A double diagnosis and a public appeal for help Natalie Moloney, a 45-year-old mother of five from Bray, faced a gruelling start to 2023 after learning she had cancer in both breasts. Doctors diagnosed an ER-positive cancer in her right breast and a triple-negative cancer in her left, describing it as a stage 3 bilateral…