Tag: endosome
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Disabling a Cellular ‘Entry Code’ Could Stop Deadly Rotavirus Infection
New Target in the War Against Rotavirus Rotavirus remains a leading cause of severe dehydrating diarrhea in infants and young children, claiming more than 128,500 lives globally each year despite broad vaccination efforts. In the United States, a worrying trend toward waning vaccine uptake has coincided with rising rotavirus cases in recent years. A team…
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Discovery opens up new avenues for treating rotavirus infections
Groundbreaking Insight into Rotavirus Infection Rotavirus remains a leading cause of severe dehydrating diarrhea in infants and young children worldwide, claiming hundreds of thousands of lives annually despite vaccination efforts. In recent years, declining vaccination uptake in some regions has contributed to a troubling rise in cases in the United States. A new study from…
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Discovery Opens New Avenues for Treating Rotavirus Infections
New Insight Into How Rotavirus Enters Cells Rotavirus remains a leading cause of severe dehydrating diarrhea in infants and young children, contributing to over 128,000 deaths annually worldwide despite widespread vaccination efforts. A new study from Washington University School of Medicine in St. Louis sheds light on a crucial step in the virus’s infection process,…
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Disabling a Critical Cellular Pathway Could Be Key to Stopping Deadly Rotavirus Infection
New findings pinpoint a host enzyme as the Achilles’ heel of rotavirus Rotavirus remains a leading cause of dehydration and severe diarrhea in infants and young children, claiming thousands of young lives each year despite vaccination efforts. A recent study from Washington University School of Medicine in St. Louis has identified a host cell enzyme,…
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Rotavirus Infection: New Host-Targeting Therapy Avenues
Overview: A new angle in the fight against rotavirus Rotavirus remains a leading cause of severe dehydrating diarrhea in infants and young children worldwide, responsible for thousands of deaths annually despite vaccines. Recent work from Washington University School of Medicine in St. Louis has spotlighted a host-based vulnerability that rotavirus exploits to infect cells. By…