Tag: early breast cancer
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Streamlining care through patient navigation: a retrospective cohort study of timely anti-HER2 therapy in early breast cancer in a LMIC
Introduction Early HER2-positive breast cancer requires timely initiation of anti-HER2 therapy to optimize outcomes. In low- and middle-income countries (LMICs), health-system constraints—ranging from diagnostic delays to treatment access barriers—can slow this process. This retrospective cohort study examines whether a structured Patient Navigation Program (PNP) can reduce the time from diagnosis to initiation of anti-HER2 therapy…
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SUPREMO Trial: Rethinking Postmastectomy Radiotherapy
Overview: A Shift in Postmastectomy Strategy The international phase 3 SUPREMO trial is reshaping how clinicians treat intermediate-risk early breast cancer (eBC) after mastectomy. The study, officially registered as ISRCTN61145589, investigated whether omitting chest-wall irradiation could maintain survival outcomes while reducing treatment-related toxicity. Historically, postmastectomy radiotherapy (PMRT) has been standard care for various levels of…