Tag: drug interactions
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Older Adults on Tramadol and Antidepressants Face Higher Seizure Risk, Study Finds
New findings link tramadol and certain antidepressants to increased seizure risk in older adults A recent study published in Neurology®, the medical journal of the American Academy of Neurology, investigated whether older adults living in nursing homes who are prescribed the pain drug tramadol alongside certain antidepressants might face a higher risk of seizures. The…
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Older Adults in Nursing Homes Face Higher Seizure Risk When Taking Tramadol With Certain Antidepressants
New Findings Spotlight Drug Interaction risk for older adults A study published on October 8, 2025, in Neurology®, the journal of the American Academy of Neurology, highlights a modest but measurable increase in seizure risk when the pain medicine tramadol is prescribed alongside certain antidepressants in older adults living in nursing homes. While the research…
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Common Pitfalls of Polypharmacy in Heart Failure and Mortality Risk
Understanding the Mortality Link: Polypharmacy in Heart Failure Polypharmacy, defined as the use of multiple medications, is common among patients with heart failure. A 2022 study found that polypharmacy is significantly associated with higher mortality, with a relative risk of 1.31 (95% CI 1.07–1.61). Notably, this risk appears most pronounced when multiple non-guideline-directed drugs are…
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Common Pitfalls of Polypharmacy in Heart Failure
What polypharmacy means for heart failure Polypharmacy, or taking multiple medications, is common among people living with heart failure. While many drugs are essential to manage symptoms and prevent progression, a heavy or uncoordinated medication load can introduce interactions and adverse effects that worsen outcomes. Recent evidence suggests that polypharmacy is significantly associated with higher…
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Respiratory Infections Surge: Medications That Can Worsen a Patient’s Condition
Respiratory Infections Surge as Weekly Cases Approach 40,000 In the past month, referring to the latest public health data, acute respiratory infections (IRAS) have surged, with weekly counts edging toward 40,000 cases. The uptick began in epidemiological week 33 (late August), when authorities recorded 33,143 episodes. One week later, the tally rose to 35,857, and…