Tag: Drug Discovery
-
New Computer-Driven Insights Reveal How Protein Patterns Shape Cell Membranes
Unveiling the Hidden Architecture of Membrane Proteins Membrane proteins are essential gatekeepers and signal transmitters in the body, guiding what enters and exits cells, orchestrating chemical reactions, and helping tissues adhere. When these proteins malfunction, diseases including cancer can arise. Despite their importance, studying them has long been a challenge because they reside in the…
-
Gly-X6-Gly Motif Reveals Membrane Protein Rules in Cells
Unraveling the Mysteries of Membrane Proteins Membrane proteins are essential gatekeepers of the cell, orchestrating substance transport, signal transduction, and intercellular adhesion. When their function goes awry, diseases such as cancer can arise, making these proteins prime targets for therapies. Yet studying membrane proteins is notoriously difficult because their lipid surroundings help them hide their…
-
AI, Omics, and Systems Biology: A New Era for Heart Drug Discovery
Reinventing Heart Drug Discovery with AI and Omics Cardiovascular disease (CVD) remains the world’s leading cause of death, despite decades of medical advances. A new perspective from Brigham and Women’s Hospital and Harvard Medical School argues that the future of heart drug development lies in an integrated, data-driven framework. By combining artificial intelligence (AI), omics…
-
AI helps Ont. researcher discover breakthrough antibiotic treatment for bowel disease
Ontario researchers leverage AI to advance Crohn’s and IBD treatment In a notable example of how artificial intelligence is accelerating medical progress, a McMaster University team, in collaboration with researchers from the Massachusetts Institute of Technology, has used AI to identify a promising new antibiotic treatment for Crohn’s disease and inflammatory bowel disease (IBD). The…
-
IU Researchers Combine Sound Waves And AI To Power Faster Biomedical Research
AI-Driven Acoustofluidics: A New Era for Biomedical Research Researchers at the Indiana University Luddy School of Informatics, Computing and Engineering are blending acoustofluidics with artificial intelligence to accelerate biomedical discovery. Acoustofluidics, the manipulation of cells and chemical components in liquids using sound waves, sits at the intersection of physics, engineering and biology. Led by Feng…
-
IU Research Combines Sound Waves And AI To Power Faster Biomedical Research
Introduction Researchers at Indiana University’s Luddy School of Informatics, Computing and Engineering are pushing the boundaries of biomedical research by marrying acoustofluidics with artificial intelligence. Acoustofluidics—the manipulation of cells and other biological materials in liquid using sound waves—has long promised a label-free, contactless way to handle delicate biological materials. By integrating AI into this platform,…
-
Stonefish Venoms May Yield New Medications, Researchers Say
Stonefish Venoms: A New Frontier in Drug Discovery Researchers from James Cook University (JCU) and the Australian Institute of Tropical Health and Medicine (AITHM) have identified immunosuppressive properties in the venoms of two stonefish species. The finding adds to a growing body of work suggesting animal venoms can be a rich source of biologically active…
-
A New Tool in the Fight Against Chronic Pain: The Quest for an Opioid-Sparing Drug
Chronic Pain and the Push for Safer Relief Chronic pain affects millions and tests the limits of modern medicine. For decades, powerful opioids have been the go-to option when other treatments fail. But the dangers—dependence, respiratory risks, and a troubling side-effect profile—have spurred an urgent search for better solutions. In this landscape, a new line…
-
A New Tool in the Battle Against Chronic Pain? The Opioid-like Breakthrough
Introduction: A new tool in the fight against chronic pain Chronic pain remains one of medicine’s toughest challenges, draining quality of life and straining healthcare systems. For decades, researchers have sought an analgesic that matches the power of the strongest opioids without the devastating side effects—addiction, respiratory depression, constipation, and misuse. A growing line of…