Tag: drug design
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Membrane Protein Function: Computational Strategy Illuminated
New Computational Strategy Sheds Light on Membrane Protein Function Membrane proteins orchestrate essential cellular tasks, from moving substances across the lipid bilayer to transmitting signals and aiding cell-to-cell interactions. When these proteins malfunction, it can lead to diseases including cancer, making them prime targets for therapeutics. Yet studying their behavior is notoriously challenging because their…
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Researchers Unveil How a Membrane Protein Motif Stabilizes Protein Architecture
New Insights into Membrane Protein Architecture Scientists at Scripps Research have unlocked fresh understanding of how membrane proteins—crucial players in transport, signaling, and cellular adhesion—achieve and maintain their complex shapes within the cell’s lipid envelope. Published in the Proceedings of the National Academy of Sciences on October 7, 2025, the study presents a computer-guided approach…