Tag: drug delivery
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Focused Ultrasound Passes First Test in Treatment of Brain Cancer in Children
What is focused ultrasound and why it matters Focused ultrasound is a non-invasive technique that uses precisely targeted sound waves to temporarily and safely disrupt the barriers protecting the brain. By transiently opening the blood-brain barrier, it can enhance the delivery of chemotherapy and other therapeutics directly to brain tissue. This approach holds particular promise…
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MIT lipid nanoparticle boosts mRNA vaccine efficacy
Overview A new lipid nanoparticle delivery particle developed at MIT could transform how mRNA vaccines are delivered, potentially improving effectiveness while reducing the amount of active ingredient needed per dose. The research, described in early-stage studies, centers on refining the particle that ferries the mRNA into cells, a crucial step in vaccine performance. What the…
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Breakthrough Eye Drop Nanomedicine Secures Worldwide Patents
Breakthrough in Eye Care: International Patents for Nanomedicine Eye Drops In a landmark development for ophthalmology and patient care, SETU Researcher Dr. Laurence Fitzhenry and the Ocular Therapeutics Research Group (OTRG) at South East Technological University have secured two international patents for advanced eye drop technology. Granted by the United States and European patent offices,…
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Cyclic peptide nanotubes offer new route to overcome cancer drug resistance
H2: Groundbreaking approach uses cyclic peptide nanotubes to deliver doxorubicin to cancer cell nuclei A team at CiQUS (University of Santiago de Compostela, Spain) has unveiled a novel molecular strategy that enables anticancer drugs to reach the nucleus of tumor cells, enhancing their therapeutic impact. Focusing on doxorubicin, a cornerstone chemotherapy drug, the researchers show…
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Innovative Approaches Target PAR2 Receptor to Alleviate Gut Pain
New Avenues in the Fight Against Gut Pain Abdominal pain is a defining feature of many digestive disorders, including inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). As researchers search for treatments that specifically address gut pain, two complementary lines of evidence are emerging. First, a newly identified bacterial enzyme may regulate pain signaling…
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Targeting PAR2: Innovative Pathways to Relieve Gut Pain
New Insights into a gut pain signaling axis Abdominal pain is a common thread across many digestive disorders, from inflammatory bowel disease (IBD) to irritable bowel syndrome (IBS). Recent research has zeroed in on PAR2, a receptor located on the gut lining and pain-sensing nerves, as a pivotal driver of gut pain. PAR2 becomes activated…
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Targeting PAR2: A Two-Pronged Strategy Uses Bacterial Enzymes and Nanoparticles to Fight Gut Pain
New Avenues in Gut Pain Management Abdominal pain is a defining symptom of many digestive disorders, from inflammatory bowel disease (IBD) to irritable bowel syndrome (IBS). A pair of pioneering studies is pushing the boundaries of how researchers might treat gut pain by focusing on PAR2, a receptor that drives pain signaling in the gut.…
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Bacillus subtilis Survives Space Launch: Microbes Endure
Groundbreaking finding: microbes can endure the brutal journey into space A new, world-first study led by Australian researchers demonstrates that the spores of Bacillus subtilis, a bacterium important for human health, can survive the punishing conditions of a suborbital space flight. The experiment blasted these hardy microbes to the edge of space in a sounding…
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DNA Manipulation with Electric Fields: McGill RECON Device
Revolutionizing DNA analysis with a touch-free approach Researchers at McGill University have introduced a new device that traps and studies DNA molecules using carefully tuned electric fields—without physical contact or damage. Built in the Department of Physics and developed in collaboration with students in Professor Walter Reisner’s Nanobiophysics lab, the tool leverages reversible electrokinetic confinement…