Tag: Down Syndrome
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HSE apologises over death of girl with Strep A infection and launches KATE training initiative
HSE apologises and a family’s call for change after Kate Colum’s death The HSE has formally apologised to the family of five-year-old Kate Colum, who died after a severe Strep A infection at Sligo University Hospital (SUH). The inquest, which concluded with a unanimous verdict of medical misadventure, highlighted serious concerns about the management of…
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HSE apologises over death of girl with Strep A infection
HSE apologises to family of five-year-old Kate Colum and signals reform The Health Service Executive (HSE) has formally apologised to the family of Kate Colum, a five-year-old girl from Strokestown, Co Roscommon, who died following a severe Strep A infection at Sligo University Hospital (SUH). The inquest outcome, delivered after more than two years of…
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HSE apologises to family of girl who died from Strep A infection in Sligo hospital case
Background: a tragic death and an inquest The Health Service Executive (HSE) has publicly apologised to the family of Kate Colum, a five-year-old girl from Strokestown, Co Roscommon, who died following a severe Strep A infection linked to organ dysfunction and septic shock. The inquest at an Dublin court concluded that medical misadventure was a…
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Centromere Balance Explains Why Some Embryos Stall During Development
Centromeres as Gatekeepers in Early Development When a sperm fertilizes an egg, the resulting zygote must reorganize parental DNA into a unified genome before the first cell division. A key, but often overlooked, player in this process is the centromere, the chromosome region that helps pull sister chromatids apart during division. For years, scientists assumed…
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Hidden DNA Process Linked to Down Syndrome and Miscarriages
What is the hidden DNA process and why it matters Researchers are studying a little-known aspect of genetic biology that governs how chromosomes are separated when eggs and sperm are formed. A surprising number of miscarriages, cases of infertility, and instances of Down syndrome can be traced back to errors in this process, errors that…
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Miscarriages, Down Syndrome, and Infertility Linked to Hidden DNA Process
Unveiling a hidden DNA process in reproduction For years, scientists have known that errors in chromosome numbers can derail pregnancy, leading to miscarriages or conditions such as Down syndrome. Now researchers are shining a light on a set of intricate, often unseen molecular steps that govern how eggs and sperm inherit their chromosomal baggage. The…
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Hidden DNA Process Tied to Miscarriages, Down Syndrome
What is the hidden DNA process behind miscarriages and infertility? A little-noticed DNA process governs how chromosomes are distributed when eggs and sperm are formed. This process, rooted in the biology of meiosis, ensures that offspring inherit the correct number of chromosomes. When it falters, the result can be aneuploidy — cells with too many…