Tag: deleterious variants
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Bovine Paratuberculosis RNA-Seq: Deleterious Variants Identified
Overview: Using RNA-Seq to Elucidate Genetic Susceptibility to Bovine Paratuberculosis Bovine paratuberculosis, a chronic intestinal disease caused by Mycobacterium avium subspecies paratuberculosis (MAP), poses significant economic and animal welfare challenges in cattle herds worldwide. Recent advances in RNA sequencing (RNA-Seq) enable researchers to explore the full transcriptome of affected and at-risk animals, with a focus…
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Bovine Paratuberculosis: Deleterious Variants by RNA-Seq
Understanding the Challenge: Paratuberculosis in Cattle Bovine paratuberculosis, caused by Mycobacterium avium subsp. paratuberculosis (MAP), is a chronic intestinal disease that affects dairy and beef cattle worldwide. It impairs productivity, reduces milk yield, and presents significant economic and welfare concerns for producers. While environmental and management factors influence infection, host genetics also plays a pivotal…