Tag: CYP2D6
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Personalized TAMENDOX Therapy Boosts Tamoxifen Effectiveness in Early Breast Cancer
Introduction: A new twist in tamoxifen treatment Breast cancer remains the most commonly diagnosed cancer among women worldwide. In a decisive step toward more effective hormone therapy, the Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology (IKP) has unveiled TAMENDOX, a personalized treatment strategy designed to optimize tamoxifen’s impact for individual patients. This multicenter clinical study…
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Personalized TAMENDOX Therapy Boosts Tamoxifen Effectiveness in Early-Stage Breast Cancer
New Personalized Therapy Aims to Improve Tamoxifen Effectiveness Breast cancer remains the most common cancer among women worldwide, and hormone receptor–positive cancers account for a significant portion of cases. In a notable advance, researchers at the Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology (IKP) have developed a personalized therapy designed to boost the effectiveness of…
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New Personalized Therapy Boosts Tamoxifen Effectiveness in Breast Cancer Patients
Overview Breast cancer remains the most common cancer among women worldwide. Recent advances from the Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology (IKP) introduce a new personalized therapy, TAMENDOX, designed to tailor hormone treatment to individual patients. The goal is to improve the effectiveness of tamoxifen, a long-standing drug used to treat hormone-dependent breast cancer,…
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Older Adults on Tramadol and Antidepressants Face Higher Seizure Risk, Study Finds
New findings link tramadol and certain antidepressants to increased seizure risk in older adults A recent study published in Neurology®, the medical journal of the American Academy of Neurology, investigated whether older adults living in nursing homes who are prescribed the pain drug tramadol alongside certain antidepressants might face a higher risk of seizures. The…
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Older Adults in Nursing Homes Face Higher Seizure Risk With Tramodol and Some Antidepressants
New Findings on Drug Interactions in Senior Care A study published on October 8, 2025, in Neurology®, the medical journal of the American Academy of Neurology, reports a modest but meaningful link between taking tramadol for pain and certain antidepressants that inhibit the CYP2D6 enzyme in older adults living in nursing homes. The researchers found…
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Older Adults in Nursing Homes Face Higher Seizure Risk When Taking Tramadol With Certain Antidepressants
New Findings Spotlight Drug Interaction risk for older adults A study published on October 8, 2025, in Neurology®, the journal of the American Academy of Neurology, highlights a modest but measurable increase in seizure risk when the pain medicine tramadol is prescribed alongside certain antidepressants in older adults living in nursing homes. While the research…