Tag: CUL5


  • CUL5: The Brain’s Garbage Collector That Clears Toxic Tau and Shields Neurons

    CUL5: The Brain’s Garbage Collector That Clears Toxic Tau and Shields Neurons

    New Discovery: A Brain Cleanup Crew Called CUL5 Scientists at the University of California, San Francisco, have identified a cellular mechanism that acts like a waste collector in the brain. The protein CUL5 appears to help neurons dispose of toxic tau clumps, which are a hallmark of several neurodegenerative diseases and a major driver of…

  • Brain Guardian: How CUL5 Clears Tau Clumps to Protect Neurons

    Brain Guardian: How CUL5 Clears Tau Clumps to Protect Neurons

    Overview: A New Player in the Brain’s Waste Management In a landmark study from UC San Francisco, scientists have identified a crucial cellular picker-upper in the brain—CUL5—that helps clear toxic tau clumps. These clumps are notorious for driving neurodegenerative diseases and dementia. By acting as a molecular garbage collector, higher levels of CUL5 in neurons…

  • How CUL5 Protects Neurons by Clearing Toxic Tau Clumps

    How CUL5 Protects Neurons by Clearing Toxic Tau Clumps

    New Discovery: CUL5 as a Cellular Garbage Collector Neurons face daily threats from misfolded proteins that can aggregate into toxic clumps. In recent research from the University of California, San Francisco, scientists have identified a crucial player in the brain’s defense against these harmful tau clumps: a protein known as CUL5. This discovery positions CUL5…