Tag: Cryo-electron microscopy
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Cryo-imaging Breakthrough Reveals Thick Biological Structures with Greater Clarity
Overview: A New Window into Thick Biological Samples Cryo-imaging has long promised a clearer view of biological materials in their near-native state. Traditional electron microscopy, while superb for isolated molecules, struggles with thicker samples. A Cornell-led team has unveiled a transformative method—tilt-corrected bright-field scanning transmission electron microscopy (tcBF-STEM)—that delivers higher contrast and dramatically increased efficiency…
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Cryo-imaging Reveals Deeper View of Thick Biological Materials
A New Window into Thick Biological Samples Cryo-imaging has taken a notable leap forward with a method called tilt-corrected bright-field scanning transmission electron microscopy (tcBF-STEM). Developed by a team at Cornell, this technique enables high-contrast imaging of thick biological materials that were previously challenging to study with electron microscopy. By rethinking how detectors capture electrons…