Tag: CRISPR
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CRISPR Brings Back Ancient Gene That Could Cut Gout and Fatty Liver Risk
Rewriting a Missing Chapter in Human Biology In a surprising turn for genetic science, researchers using CRISPR gene-editing tools have revived a gene that disappeared from the human lineage millions of years ago. The restored gene appears to play a role in regulating uric acid production and lipid metabolism, two factors closely tied to gout…
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CRISPR Resurrects Ancient Gene to Fight Gout and Fatty Liver
CRISPR Brings Back an Ancient Gene With Modern Implications A recent report in Scientific Reports unveils a bold genetic experiment: scientists used CRISPR gene-editing tools to revive a gene that vanished from the human lineage millions of years ago. The revived gene appears to modulate purine metabolism and uric acid production, leading to lower uric…
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CRISPR Restores Ancient Gene to Cut Uric Acid and Fight Gout and Fatty Liver
Introduction: A bold leap from ancient DNA to modern health In a striking demonstration of CRISPR gene-editing tools, researchers have resurrected an ancient human gene that disappeared from the genome millions of years ago. The restored gene, when expressed in a controlled laboratory setting, lowered uric acid levels and showed promising indications for reducing risks…
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First-in-Human Trial: CTX310 Gene-Editing Therapy Halves Bad Cholesterol
Groundbreaking Step in Lipid Disorder Treatment In a landmark development for cardiovascular health, researchers in Australia have initiated a first-in-human trial of CTX310, a gene-editing therapy designed to dramatically reduce bad cholesterol (LDL) and triglycerides in individuals with difficult-to-treat lipid disorders. Early results suggest the therapy can halve levels of harmful lipids, offering a potential…
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CRISPR Gene-Editing Shows Promise in Lowering Cholesterol in Early Study
New CRISPR-based therapy reduces cholesterol in a small early study A recent small-stage study has sparked cautious optimism in the fight against high cholesterol. Researchers tested an experimental gene-editing therapy delivered by a single infusion to participants with elevated cholesterol levels. The approach uses CRISPR gene editing to target and alter the body’s pathways that…
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CRISPR Breakthrough: Gene-Editing Drug Lowers High Cholesterol in Early Trial
New Hope for High Cholesterol: A First Look at a CRISPR-Based Therapy In a small, early-stage study, researchers tested an experimental gene-editing drug designed to lower levels of LDL cholesterol, the type often linked to heart disease. The trial involved 15 volunteers who received a single infusion. While the study is preliminary, the findings suggest…
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CRISPR Gene Editing Shows Promise in Lowering Cholesterol in Initial Study
CRISPR Gene Editing: A Bold Step in Cholesterol Management Scientists are exploring a groundbreaking approach to fighting high cholesterol using CRISPR gene-editing technology. In a small, early clinical trial, researchers administered a single infusion of an experimental gene-editing drug to a group of volunteers with elevated cholesterol. The results offered a glimmer of hope that…
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Scientists Edge Toward Reversing Memory Loss in Aging Brains with Gene Editing
New Frontiers in Memory and Aging Scientists are moving closer to a breakthrough in how aging brains can regain memory function. In two complementary studies led by Timothy Jarome, associate professor in the College of Agriculture and Life Sciences’ School of Animal Sciences, researchers used advanced gene-editing tools to target molecular changes associated with memory…
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Advancing Gene Editing: How Lipid Nanoparticles Are Shaping CRISPR Delivery
Introduction: The delivery bottleneck in CRISPR therapies CRISPR-based medicines hold the promise of treating a wide range of diseases, but their success hinges on effective delivery. Early efforts relied on viral vectors, especially adeno-associated viruses (AAVs), to ferry genetic material. While AAVs can deliver DNA, their payload size is limited and пациентов often develop immune…
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Advancing Gene Editing: The Role of Lipid Nanoparticles in CRISPR Delivery
Introduction: Why delivery platforms matter in CRISPR medicine CRISPR-based therapies hold immense promise for treating a wide range of diseases, but their success hinges not only on the gene-editing tool itself but also on how the therapeutic payload reaches target cells. With nucleic acid–based CRISPR medicines, delivery is as crucial as the editing technology. While…