Tag: CRC


  • The Dual Role of SLC7A11 in Colorectal Cancer Ferroptosis: From Molecules to Therapies

    The Dual Role of SLC7A11 in Colorectal Cancer Ferroptosis: From Molecules to Therapies

    Understanding Ferroptosis and SLC7A11 Ferroptosis is a regulated form of cell death driven by iron-dependent lipid peroxidation. In colorectal cancer (CRC), ferroptosis represents a promising avenue to overcome resistance to conventional therapies. Central to this process is SLC7A11, a component of the cystine/glutamate antiporter system Xc–, which imports cystine into cells in exchange for glutamate.…

  • The Dual Role of SLC7A11 in Colorectal Cancer Ferroptosis: A Molecular Tug-of-War

    The Dual Role of SLC7A11 in Colorectal Cancer Ferroptosis: A Molecular Tug-of-War

    Understanding Ferroptosis and SLC7A11 in Colorectal Cancer Colorectal cancer (CRC) remains a major global health challenge, driven by complex metabolic and genetic alterations. A relatively new area of cancer biology—ferroptosis—refers to an iron-dependent form of regulated cell death triggered by lipid peroxidation. At the center of this process lies SLC7A11, a cystine/glutamate antiporter, which plays…

  • Should Ghana Lower Its Presidential Age? Experts Debate 30-Year-Old Leaders

    Should Ghana Lower Its Presidential Age? Experts Debate 30-Year-Old Leaders

    Introduction: The Age Debate in Ghana’s Presidency Ghana’s constitutional reform conversations have reignited around a provocative question: should the minimum age for presidential candidates be lowered from 40 to 30? The Constitutional Review Committee (CRC) recommended a reduction, arguing that younger generations deserve a stronger voice in national leadership. Yet prominent voices in governance and…

  • Cybercrime Surge Drives P1B DICT Budget Boost, Says Brian Poe

    Cybercrime Surge Drives P1B DICT Budget Boost, Says Brian Poe

    Overview: Why the DICT budget is back in the spotlight The Philippines is lining up a sizable budget response to a sharp rise in cybercrime. FPJ Panday Bayanihan Party-list Rep. Brian Poe, a vice chair of the Committee on Appropriations, argued during the marathon plenary debates on the P6.793‑trillion General Appropriations Bill (GAB) for 2026…

  • Poe pushes P1B DICT security budget amid cybercrime surge

    Poe pushes P1B DICT security budget amid cybercrime surge

    Poe pushes P1B DICT security budget amid cybercrime surge The surge in cybercrime has lawmakers calling for stronger digital defense. FPJ Panday Bayanihan Party-list Rep. Brian Poe, a vice chairman of the Committee on Appropriations, presented the case for boosting the Department of Information and Communications Technology (DICT) budget for 2026 as part of the…

  • Cybercrime Surge Spurs P1B DICT Security Budget Boost, Poe Says

    Cybercrime Surge Spurs P1B DICT Security Budget Boost, Poe Says

    Cybercrime Surge Spurs P1B DICT Security Budget Boost, Poe Says The surge in cybercrime has become a rallying cry for a bigger shield around the Philippines’ digital landscape. FPJ Panday Bayanihan Party-list Rep. Brian Poe, a vice chairman of the Committee on Appropriations and the budget sponsor for the Department of Information and Communications Technology…