Tag: clinical trials
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Apnimed Announces Lancet Publication: Positive Phase 2 Results for Sulthiame in Obstructive Sleep Apnea
New Lancet Publication Highlights Positive Phase 2 Outcomes Apnimed has revealed breakthrough findings from its Phase 2 FLOW study, showing that sulthiame, an oral carbonic anhydrase inhibitor, met the primary endpoint across all doses tested in obstructive sleep apnea (OSA). The Lancet publication details how sulthiame not only achieved statistical significance on primary measures but…
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Knowledge Domain and Emerging Trends on Dapagliflozin for Heart Failure: A Bibliometric View (2012–2024)
Introduction: Dapagliflozin as a Cornerstone in Heart Failure Therapy Heart failure (HF) remains a global healthcare challenge with rising prevalence and substantial economic burden. Dapagliflozin, an SGLT2 inhibitor, emerged as a pivotal therapy beyond glucose control, driven by landmark trials such as DAPA-HF. A bibliometric analysis of research from 2012 to 2024 reveals how scientific…
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Knowledge Gaps and Emerging Trends in Dapagliflozin for Heart Failure: A 2012–2024 Bibliometric Analysis
Introduction Dapagliflozin, a pioneering SGLT2 inhibitor, has evolved from a diabetes medication to a cornerstone therapy for heart failure (HF). Built on pivotal trials such as DAPA-HF and DELIVER, its role now spans reduced and preserved ejection fraction HF subtypes, with ongoing investigations into cardiorenal protection and fibrosis modulation. This article interprets a comprehensive bibliometric…
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Funding the Frontier: An AI tool mapping research funding to patents, policies, and trials
What is Funding the Frontier? Funding the Frontier (FtF) is a new machine learning-based tool designed to illuminate how research funding translates into real-world outcomes. While traditional assessments focus on grants and scholarly papers, FtF traces a broader impact—from patents and clinical trials to policies and news coverage—across a vast network of data. The goal…
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AI Tool Maps Research Funding Impact From Grants to Patents and Policies
Overview: A New AI Lens on Research Funding Billions are invested globally in scientific research each year. Yet pinpointing where that money ends up—whether in publications, patents, clinical trials, or policy shifts—has remained challenging. A new machine learning tool, Funding the Frontier (FtF), aims to fix that gap by mapping grant funding to a broad…
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AI tool maps research funding impact from grants to patents, policies and clinical trials
Overview: A new way to track how research funding moves from investment to real-world outcomes Every year, billions are invested worldwide to fuel discovery. Yet funding decisions are often evaluated through a narrow lens—focused on publications and grants—missing the broader ripple effects that shape innovation, policy, and health. A new machine learning tool, Funding the…
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Telford cancer patient raises £120k for liver chemotherapy
NHS worker in Telford seeks £120,000 for liver-directed chemotherapy A 49-year-old NHS communications worker from Telford is crowdfunding £120,000 to access a high-dose chemotherapy treatment for ocular melanoma that has spread to the liver. Jamie Scott, diagnosed with eye cancer in 2011, has faced a barrier within the health system that has left her unable…
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Could COVID mRNA Vaccines Help Fight Cancer? New US Study Sparks Hope—and Caution
Can COVID mRNA vaccines boost cancer treatment? Recent research from the United States has sparked interest in a surprising possible benefit of the COVID-19 mRNA vaccine: enhancing the effectiveness of cancer immunotherapy. In a retrospective analysis of more than 1,000 patient records, researchers found that patients with advanced lung cancer or metastatic skin cancer (melanoma)…
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Global Lobular Breast Cancer Awareness Day Highlights Need for Improved Detection and Treatment
Raising Awareness for a Less-Recognized Breast Cancer Subtype Last week, lobular breast cancer patients and their providers gathered at Fred Hutch Cancer Center for a two-hour program timed to Global Lobular Breast Cancer Awareness Day. The event highlighted patient stories, epidemiological findings, and the latest developments in screening and clinical trials for invasive lobular carcinoma…
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Advancing Awareness and Innovation in Invasive Lobular Breast Cancer: Lessons from a Fred Hutch Event
Global Lobular Breast Cancer Day shines spotlight on ILC challenges and breakthroughs Last week, invasive lobular breast cancer (ILC) patients and their care teams gathered at Fred Hutch Cancer Center for a focused two-hour program. The event, held on October 15 to mark Global Lobular Breast Cancer Awareness Day, brought patient stories, epidemiological insights, and…