Tag: Chemotherapy
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Treating Head and Neck Squamous Cell Carcinoma with Intratumoral Bacteria: New Hope from Radiation and Chemotherapy Advances
Understanding the Breakthrough Head and neck squamous cell carcinoma (HNSCC) is a challenging cancer type, often requiring aggressive radiation and chemotherapy regimens. Recent research, including an international multicenter trial led by MSK radiation oncologist Dr. Nancy Lee, has explored a provocative idea: bacteria residing inside tumors can impact how cancer responds to standard treatments. This…
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Treatment for Head and Neck Squamous Cell Carcinoma Affected by Bacteria Inside the Tumors: New Insights from MSK-LED Trial
Understanding intratumoral bacteria in head and neck cancer Head and neck squamous cell carcinoma (HNSCC) is a challenging disease that often requires a combination of radiation and chemotherapy. Recently, scientists have begun investigating an unexpected factor that could influence treatment outcomes: bacteria living inside tumors. This intratumoral microbiome may shape how tumors respond to therapy,…
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Intratumoral Bacteria and the Future of Head and Neck Squamous Cell Carcinoma Treatment: Insights from a Pioneering Trial
Understanding the Role of Intratumoral Bacteria in Head and Neck Squamous Cell Carcinoma Head and neck squamous cell carcinoma (HNSCC) remains a challenging cancer to treat, with outcomes closely tied to tumor biology and the surrounding microenvironment. A growing area of research focuses on the microbiome that resides within tumors — the intratumoral bacteria. Recent…
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Ocular Melanoma Liver Chemotherapy Funding: NHS Access Challenge in Telford
Hooked by a life-changing diagnosis Jamie Scott, a 49-year-old communications worker for an NHS mental health trust, was diagnosed with eye cancer (ocular melanoma) in 2011. Over the years the cancer has progressed, spreading to her liver and triggering a fierce fight not just against the disease but against the barriers that limit timely access…
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Cyclic peptide nanotubes offer new route to overcome cancer drug resistance
H2: Groundbreaking approach uses cyclic peptide nanotubes to deliver doxorubicin to cancer cell nuclei A team at CiQUS (University of Santiago de Compostela, Spain) has unveiled a novel molecular strategy that enables anticancer drugs to reach the nucleus of tumor cells, enhancing their therapeutic impact. Focusing on doxorubicin, a cornerstone chemotherapy drug, the researchers show…
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From Swelling to Survival: Irish Singer McDonnell’s Journey Through Breast Cancer and Beyond
Early Signs and the Importance of Self-Awareness Breast cancer is the most common cancer among women in Ireland, a fact underscored by the experiences shared by an Irish singer who navigated a sudden shift from mild swelling to a life-changing diagnosis. As Helen Forristal, director of nursing services with the Marie Keating Foundation, stresses, “One…
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Pembrolizumab Doubles Survival in Advanced Head and Neck Cancer
The Breakthrough: A New Immunotherapy Redefines Outcomes in Locally Advanced Head and Neck Cancer Locally advanced head and neck cancer poses a formidable challenge. In many patients, the disease is detected at a stage where surgery, radiotherapy, and chemotherapy are the mainstays of treatment, yet recurrence and progression remain common. A recent advance in immunotherapy,…
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Bray mum-of-five beats bilateral breast cancer after two-year battle
Diagnosis and a public plea for help In October 2023, Natalie Moloney, a 45-year-old mum from Bray, County Wicklow, was diagnosed with ER-positive cancer in her right breast and triple-negative cancer in her left breast, at stage 3. She described it as a “double whammy of bilateral breast cancer” and, with her family, decided to…
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Bray mum-of-five celebrates all-clear after bilateral breast cancer battle
A double diagnosis and a public appeal for help Natalie Moloney, a 45-year-old mother of five from Bray, faced a gruelling start to 2023 after learning she had cancer in both breasts. Doctors diagnosed an ER-positive cancer in her right breast and a triple-negative cancer in her left, describing it as a stage 3 bilateral…
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Nosebleeds to cancer: A man’s journey
Understanding nasopharyngeal cancer Nasopharyngeal cancer (NPC) is a cancer that originates in the nasopharynx, the upper part of the throat behind the nose. In Singapore, NPC remains one of the more common cancers, with roughly 300 new cases diagnosed each year. While NPC is more prevalent among Chinese men in this country, it does occur…