Tag: cell signaling
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Groundbreaking Study Identifies Key Cells Driving Tissue Regeneration After Severe Damage
New Discoveries in Regenerative Biology In a landmark study conducted at the Weizmann Institute of Science, researchers have identified the specific cells that enable severely damaged tissue to regenerate. This breakthrough marks a turning point in regenerative medicine and could reshape strategies for preventing cancer relapse, where damaged tissue repair often fails, giving malignant cells…
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How Structural Findings Explain Why GPCR Ligands Ignite Different Activation Levels
Understanding GPCRs and Their Ligands G-protein coupled receptors (GPCRs) are a vast family of cell-surface proteins that translate external chemical signals into cellular actions. Ligands—ranging from small molecules to peptides—bind to these receptors and trigger a cascade of molecular events inside the cell. The outcome can vary widely: some ligands yield a mild response, others…
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UK £3.5 Million Grant to Unravel How Cells Talk in Development
A Major Grant to Decode Cellular Conversation A landmark seven-year study has been funded with a £3.5 million Wellcome Discovery Award to investigate how cells exchange information to coordinate the formation of tissues and organs. Researchers at the Living Systems Institute (LSI) at the University of Exeter will lead this ambitious project, aiming to delineate…
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Targeting PAR2: A Two-Pronged Strategy Uses Bacterial Enzymes and Nanoparticles to Fight Gut Pain
New Avenues in Gut Pain Management Abdominal pain is a defining symptom of many digestive disorders, from inflammatory bowel disease (IBD) to irritable bowel syndrome (IBS). A pair of pioneering studies is pushing the boundaries of how researchers might treat gut pain by focusing on PAR2, a receptor that drives pain signaling in the gut.…