Tag: cancer immunology
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Myeloid-Driven Immunotherapy Resistance in Kidney Cancer: Interferon Signaling Under Scrutiny
Overview: A New Mechanism Behind Immunotherapy Resistance in Kidney Cancer Immunotherapy has transformed the treatment landscape for advanced renal cell carcinoma (RCC), but responses remain inconsistent. A landmark study published in Immunity (October 2025) by researchers including Dana-Farber Cancer Institute’s Eliezer M. Van Allen, MD, identifies a critical role for myeloid cells in shaping resistance…
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Disputation Spotlight: Unraveling Tumor-associated Adaptive NK Cells — Yizhe Sun
Overview On October 24, 2025, Yizhe Sun will defend a pivotal dissertation at Karolinska Institutet, delving into the phenotypic features and functional mechanisms of tumor-associated adaptive natural killer (NK) cells. Hosted in Lagerlöf, plan 4, inside the KI campus, the disputation brings together renowned researchers and clinicians to evaluate a significant advance in tumor immunology.…
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Glioblastoma Erodes Skull Bone and Rewrites Immune Marrow
A deadly brain cancer with systemic consequences Glioblastoma, the deadliest form of brain cancer, is not contained to the brain alone. New research from Montefiore Einstein Comprehensive Cancer Center (MECCC) and the Albert Einstein College of Medicine shows the aggressive tumor also erodes the skull bone and reshapes the skull’s immune landscape. The findings, published…