Tag: cancer genomics
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Single-Chromosome Sequencing in Human Cancers: Key Genes and Insights
Introduction: A focused lens on cancer genomics The field of cancer genetics is rapidly evolving, with researchers seeking methods that offer high-resolution insights while managing complexity. Single-chromosome sequencing represents a focused approach that targets individual chromosomes to reveal mutations, structural variations, and regulatory changes that drive tumor behavior. This review by Brian Tait, Chief Scientific…
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Single-Chromosome Sequencing in Human Cancers: Advancing Precision Oncology
Introduction: Why Focus on Single-Chromosome Sequencing? In cancer genetics, the ability to map alterations at the level of a single chromosome offers a focused lens on genomic instability, chromosomal rearrangements, and gene dosage effects. Single-chromosome sequencing (SCS) enables researchers to isolate and analyze one chromosome at a time, reducing complexity from the entire genome and…