Tag: biomarker
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Identification of Novel TERT Promoter Mutations in Chronic Hepatitis B and Hepatocellular Carcinoma Risk
Introduction Liver cancer remains a major global health challenge, with hepatocellular carcinoma (HCC) as its most common form. Chronic hepatitis B virus (HBV) infection is a leading driver of HCC, particularly in regions with high HBV prevalence. Recent research has focused on the genetic and molecular underpinnings of HBV-related liver cancer, including alterations in the…
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Concordia researchers identify key marker linking coronary artery disease to cognitive decline
New insight into how heart health shapes brain function Concordia researchers have identified a potential biomarker that links coronary artery disease (CAD) to cognitive decline, offering a possible explanation for why some individuals with heart disease experience faster cognitive aging or dementia. While CAD has long been associated with strokes and vascular-related cognitive impairment, the…
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New MAEA Function Could Tip the Scales in Chemotherapy Resistance
Groundbreaking discovery: MAEA’s unexpected role in DNA repair A University of Alberta research team has identified a surprising new function for MAEA (macrophage erythroblast attacher), a protein once thought to be primarily involved in red blood cell development. The scientists report in Science Advances that MAEA also plays a critical role in DNA repair and…
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MAEA Protein’s New Role Could Boost Chemotherapy Response
New findings reveal MAEA’s unexpected function in DNA repair and cancer therapy A University of Alberta research team has uncovered a surprising new role for the MAEA protein, historically associated with red blood cell development and linked to developmental disorders. In a study published in Science Advances, the researchers show that MAEA also helps control…