Tag: BATF2
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BATF2: Glutamine-Driven Silencing of a Novel Tumor Suppressor in Head and Neck Cancer
Introduction A groundbreaking study from researchers at The University of Texas MD Anderson Cancer Center reveals that BATF2, a newly identified tumor suppressor gene, is silenced by metabolic factors in the tumor microenvironment. Specifically, glutamine appears to suppress BATF2 activity, dampening the immune response against head and neck cancer in five preclinical models. This discovery…
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BATF2: A Novel Tumor Suppressor Silenced by Glutamine in Head and Neck Cancer
Overview: BATF2 and its role in immune surveillance Researchers from The University of Texas MD Anderson Cancer Center have identified BATF2 as a novel tumor suppressor that helps coordinate immune responses against head and neck cancers. In healthy tissue, BATF2 is part of a transcriptional network that supports anti-tumor immunity. The new work reveals that,…
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BATF2: A Glutamine-Driven Silencing of a Tumor Suppressor in Head and Neck Cancer
Overview: BATF2 as a Tumor Suppressor in Head and Neck Cancer BATF2 is emerging as a critical tumor suppressor whose activity helps mobilize the immune system against head and neck cancers. In preclinical studies led by researchers at The University of Texas MD Anderson Cancer Center, BATF2 function was consistently reduced in several models of…