Overview: Microbial Interactions in Polymicrobial Lung Infections In chronic lung diseases such as COPD, cystic fibrosis, and COPD-related bronchial infections, microbial communities often comprise multiple species whose interactions determine disease trajectory and treatment outcomes. Polymicrobial infections can amplify virulence and antibiotic resistance, complicating management. This evolving field recognizes that even low-abundance microbes can steer the…