Tag: autoantibodies


  • Cryo-EM Maps Find Autoantibody Hotspots on NMDA Receptors

    Cryo-EM Maps Find Autoantibody Hotspots on NMDA Receptors

    New insights into anti-NMDAR encephalitis Researchers have long sought to understand why the brain’s immune system sometimes attacks the N-methyl-D-aspartate receptor (NMDAR), triggering a dangerous condition known as autoimmune encephalitis or “Brain on Fire.” A recent study published in Science Advances uses high-resolution Cryo-Electron Microscopy (Cryo-EM) to map where autoantibodies latch onto NMDA receptors. The…