Tag: artemisinin resistance
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How Asia-like Artemisinin Resistance Is Emerging in Africa
Understanding the question: What is artemisinin resistance? Artemisinin-based combination therapies (ACTs) are the frontline treatment for uncomplicated malaria caused by Plasmodium falciparum. In parts of Asia, resistance to artemisinin arose when the parasite evolved mutations in the kelch13 (K13) gene, slowing parasite clearance after drug exposure. Over time, resistance also spread to partner drugs, complicating…
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New Malaria Drug Could Be a Life-Saver as Standard Treatments Show Weakness
New Hope in Malaria Treatment as Resistance Emerges Malaria, a disease that burdened humanity for centuries, is facing a troubling trend: the standard drugs that have kept transmission and mortality low are increasingly under pressure from drug-resistant parasites. Scientists are sounding the alarm and urgently seeking safer, more effective options that can keep pace with…
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New Malaria Drug Could Be a Life-Saver as Standard Therapy Shows Weakness
Rising Concern Over Artemisinin Resistance Malaria remains a leading cause of illness and death in many tropical regions. For two decades, the frontline defense has been artemisinin-based combination therapies (ACTs), built on derivatives of artemisinin, a compound discovered from the sweet wormwood plant. These drugs have dramatically reduced mortality, especially among children in sub-Saharan Africa.…