Tag: antiviral research
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Pin1 Inhibitors Could Stop Cold Sores by Reshaping Cellular Barriers
New antiviral strategy targets host cell structures to combat HSV-1 Researchers are exploring a novel class of antivirals that go beyond directly attacking viruses. Pin1 inhibitors, a group of compounds that modulate the host enzyme peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1), have shown promise in curbing herpes simplex virus 1 (HSV-1) replication. HSV-1 is the…
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Pin1 Inhibitors Offer New Hope Against Cold Sores by Altering Cell Structures
New class of antivirals targets host cell structure to block HSV-1 A promising development from recent research suggests that a class of antivirals known as Pin1 inhibitors could prevent or significantly reduce outbreaks of herpes simplex virus 1 (HSV-1), the virus behind oral herpes and cold sores. The study, published in Antiviral Research, highlights a…
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Pin1 Inhibitors Could Halt HSV-1 Outbreaks In Humans
New Pin1 Inhibitors Offer a New Way to Combat Cold Sores Researchers are exploring a novel class of antivirals that could change how we prevent and treat oral herpes. Pin1 inhibitors, designed to target a cellular enzyme called peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1), have shown potential to curb herpes simplex virus 1 (HSV-1) replication.…
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Disabling a Key Cellular Pathway: A Promising Route to Stop Rotavirus Infections
New Therapeutic Target Emerges in the Battle Against Rotavirus Rotavirus remains a leading cause of severe dehydrating diarrhea in infants and young children, responsible for hundreds of thousands of deaths annually despite widespread vaccination. In the United States and globally, changing vaccination uptake can influence the disease’s burden. A team at Washington University School of…