Tag: Antimicrobial Stewardship
-
Diagnostic, Therapeutic, and Evolutionary Profile of Salmonellosis at the CHNEAR in Dakar
Introduction Salmonellosis, caused by various serovars of the Gram-negative bacillus Salmonella, remains a major cause of gastroenteritis and invasive disease in many parts of the world. In Dakar, the CHNEAR hospital network plays a pivotal role in diagnosing and managing Salmonella infections, including typhoidal and non-typhoidal forms. This article synthesizes a diagnostic, therapeutic, and evolutionary…
-
Antibiotic De-Escalation Improves Outcomes in Community-Onset Sepsis
Overview: Rethinking Empiric Therapy in Community-Onset Sepsis Community-onset sepsis remains a critical challenge for clinicians who must balance rapid infection control with the risks of broad-spectrum antibiotic (BSA) overuse. In many cases, patients are started on empiric BSA to cover a wide range of potential pathogens. However, growing evidence supports antibiotic de-escalation as a safe…
-
Strengthening Infection Prevention and Control in Cameroon’s Obstetrics and Gynecology Department
Introduction Healthcare-associated infections (HAIs) pose a significant threat to patients and newborns in Cameroon, particularly within obstetrics and gynecology units. This article examines knowledge gaps, practical IPC measures, and how a referral hospital in Cameroon can strengthen infection prevention and control (IPC) to reduce maternal and neonatal morbidity and mortality. Effective IPC is essential to…
-
Antimicrobial Stewardship Interventions in EMRO: Outcomes Across Clinical, Economic, and Consumption Dimensions
Introduction Antimicrobial resistance (AMR) remains a pressing global health challenge, with the WHO Eastern Mediterranean Region (EMRO) facing unique burdens related to antibiotic use, stewardship implementation, and monitoring. This scoping review synthesizes the evidence on antimicrobial stewardship (AMS) interventions in EMRO countries, focusing on three core domains: clinical outcomes, economic implications, and antibiotic consumption patterns.…
-
Antimicrobial Stewardship Interventions in the WHO Eastern Mediterranean Region: A Scoping Review of Clinical, Economic, and Consumption Outcomes
Overview Antimicrobial resistance (AMR) poses a significant threat worldwide, with the WHO Eastern Mediterranean Region (EMRO) facing unique challenges due to variability in health systems, antibiotic usage, and surveillance capacity. This article summarizes findings from a comprehensive scoping review that evaluated antimicrobial stewardship (AMS) interventions across EMRO countries, focusing on three key domains: clinical outcomes,…
-
Antimicrobial Stewardship in WHO Eastern Mediterranean Region: A Scoping Review of Outcomes
Overview Antimicrobial resistance (AMR) poses a critical threat to global health, and its impact is pronounced in the World Health Organization’s Eastern Mediterranean Region (EMRO). A recent scoping review synthesizes how antimicrobial stewardship (AMS) interventions have been designed, implemented, and evaluated across EMRO countries. The study maps clinical outcomes, economic implications, and patterns of antibiotic…
-
Act Now: TrACSSing the Path to Action — AMR Progress in the Western Pacific During World AMR Awareness Week 2025
World AMR Awareness Week 2025: Why the Western Pacific Region Needs Action Now World AMR Awareness Week (WAAW) 2025 centers on the theme “Act Now: Protect Our Present, Secure Our Future.” In the Western Pacific Region, the World Health Organization (WHO) is hosting a webinar titled “TrACSSing the Path to Action — Reflections on AMR…
-
World AMR Awareness Week 2025: TrACSSing the Path to Action in the Western Pacific
World AMR Awareness Week 2025: A Call to Action World AMR Awareness Week 2025 arrives with a clear, urgent message: Act Now: Protect Our Present, Secure Our Future. This year, the World Health Organization (WHO) organizes a regional webinar for the Western Pacific to illuminate how far the region has come in the battle against…
-
Colistin Monotherapy vs Colistin-Meropenem in CRE Acquisition: AIDA Trial Findings
Background and Rationale Carbapenem-resistant Enterobacterales (CRE) pose a growing threat in healthcare settings due to limited treatment options and high mortality. Colistin, often used as a backbone of therapy, is frequently combined with carbapenems like meropenem in attempts to broaden antimicrobial activity and suppress resistance. The AIDA randomized trial investigates whether colistin monotherapy or a…
-
Impact of Clinical Factors on Nosocomial Infections and Bacterial Resistance
Introduction Nosocomial infections, also known as healthcare-associated infections (HCAIs), are infections that develop in patients during stays in healthcare facilities, typically after 48 hours of hospitalization. These infections, coupled with rising bacterial resistance, pose a major challenge to patient safety, clinical outcomes, and healthcare costs. This article examines how clinical factors—ranging from patient comorbidities to…