Tag: Aneuploidy
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Why Some Embryos Stall in Development: Centromere Clues from a New Study
Centromeres: The gatekeepers of early cell division Early embryo development hinges on a flawless handoff of parental DNA, a process that begins even before the first cell division. At the heart of this handoff are centromeres, special chromosome regions that act like handles during chromosome segregation. A key feature that marks these regions across generations…
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Centromere Balance Explains Why Some Embryos Stall During Development
Centromeres as Gatekeepers in Early Development When a sperm fertilizes an egg, the resulting zygote must reorganize parental DNA into a unified genome before the first cell division. A key, but often overlooked, player in this process is the centromere, the chromosome region that helps pull sister chromatids apart during division. For years, scientists assumed…
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Centromere Symmetry in Embryos: Why Some Embryos Stall
Centromeres and early embryo development When a sperm fertilizes an egg, the resulting zygote must quickly reassemble a unified genome from two parental sets of chromosomes. A key part of this process is the centromere, a chromosome region that acts like a handle for pulling the DNA apart during cell division. For decades, scientists believed…
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Hidden DNA Process Linked to Down Syndrome and Miscarriages
What is the hidden DNA process and why it matters Researchers are studying a little-known aspect of genetic biology that governs how chromosomes are separated when eggs and sperm are formed. A surprising number of miscarriages, cases of infertility, and instances of Down syndrome can be traced back to errors in this process, errors that…