Tag: 3D genome
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3D Maps of the Human Genome: A Landmark Leap in Genomic Architecture
Groundbreaking 3D Maps Shed Light on Genome Architecture In a landmark collaboration, Northwestern University researchers and the 4D Nucleome Project have unveiled the most detailed three‑dimensional maps of the human genome to date. These maps chart how the genome’s physical structure—its looping, folding, and spatial neighborhood—shapes gene regulation, cell identity, and disease processes. By moving…
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Researchers unveil most detailed 3D maps of the human genome
Groundbreaking 3D maps illuminate the genome’s hidden architecture In a landmark achievement, researchers from Northwestern University and the 4D Nucleome Project have released the most detailed three-dimensional (3D) maps of the human genome to date. These maps chart how the long strands of DNA fold and interact inside the nucleus, offering new insights into how…
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Groundbreaking 3D Maps of the Human Genome Reveal New Genome Architecture
Introduction: A leap forward in understanding genome architecture Researchers from Northwestern University, in collaboration with the 4D Nucleome Project, have unveiled the most detailed three‑dimensional maps of the human genome to date. This landmark work dives into the physical organization of DNA, offering unprecedented insight into how the genome’s shape influences gene regulation, development, and…
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Tiny genome loops persist through mitosis, reshaping our view of cell division
New insight into mitosis: small loops endure where larger structures fall away In a surprising turn for how we understand cell division, MIT researchers have found that tiny 3D loops in the genome persist—or even strengthen—during mitosis, the process by which a cell copies its DNA and divides into two daughter cells. This discovery challenges…
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Tiny genome loops persist in dividing cells, reshaping mitosis understanding
Overview: A surprise in the mitotic genome For decades, scientists believed that as cells prepare to divide, their chromosomes condense into a tightly packed, featureless slate. Once division finished, the genome would gradually reestablish its complex 3D structure to regulate which genes are active in each daughter cell. A groundbreaking study from MIT challenges this…
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Tiny Genome Loops Persist During Cell Division, MIT Finds
New insight into mitosis: genome structure isn’t erased For decades, scientists believed that as cells divide, the genome is stripped of its intricate 3D organization and that this structure gradually returns only after mitosis. A groundbreaking MIT study challenges that view by showing that tiny 3D loops, known as microcompartments, persist throughout cell division and…