Tag: 3D culture
-
Organoids Reveal Glioblastoma’s Evasion Tricks in Brain-Murking Mini-Tumors
New 3D organoid models bring glioblastoma closer to the living brain Glioblastoma, the most aggressive form of brain cancer, has long shown a stubborn resistance to treatments. Researchers at UCLA have developed advanced miniature 3D tumor organoid models that mirror many aspects of human brain tissue. These organoids recreate the complex interactions between glioblastoma cells…
-
Platform-Driven Spheroid Dynamics: How 3D Culture Environments Shape Pancreatic Cancer Behavior
Introduction: Why the Culture Environment Matters in Pancreatic Cancer Research Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal cancers, partly due to its complex microenvironment and resistance to chemotherapy. Traditional 2D cultures fail to capture the 3D architecture and mechanical cues that influence tumor cell behavior. In this study, researchers compared two common…