Overview
The Yale Journal of Biology and Medicine (YJBM) is announcing a dedicated issue focused on mitochondria in health and disease. This special edition invites researchers from across biology, medicine, and allied fields to contribute original research articles, comprehensive reviews, and perspective pieces exploring how mitochondrial function and dysfunction influence health, aging, metabolism, neurodegeneration, cancer, cardiovascular disease, immunology, and pharmacology.
Scope and Topics
Manuscripts should address the role of mitochondria in normal physiology and in disease states, including but not limited to:
- Mitochondrial bioenergetics, dynamics, and signaling networks
- Genetic and epigenetic regulation of mitochondrial function
- Mechanisms of mitochondrial dysfunction in neurological disorders
- Mitochondria and aging, metabolic diseases, and cancer biology
- Mitophagy, quality control, and mitochondrial biogenesis
- Therapeutic strategies targeting mitochondria, including pharmacology and gene therapy
- Non-mitochondrial organelle communication and mitochondrial cross-talk
Interdisciplinary works are encouraged, including translational studies, clinical observations, and methodological advances that enhance our understanding of mitochondrial biology.
Submission Details
The submission deadline for manuscripts is June 1, 2026, with publication planned for September 2026. Submissions should conform to YJBM’s guidelines and be prepared to undergo peer review. The editorial team seeks rigorous data, clear interpretation, and a narrative that connects mitochondrial mechanisms to health outcomes and disease processes.
Authors are encouraged to present innovative hypotheses supported by solid data, well-structured figures, and a transparent discussion on limitations and future directions. The journal welcomes works from established investigators and early-career researchers alike, fostering a diverse range of perspectives on mitochondrial biology.
How to Submit
Prospective authors should format their manuscripts according to YJBM guidelines and submit through the journal’s official portal. Include a cover letter outlining the manuscript’s significance, a concise abstract, highlights of key findings, and potential implications for clinical or biomedical research. The editorial team will acknowledge receipt and provide timelines for review.
Why Contribute
A dedicated issue on mitochondria in health and disease offers an opportunity to share cutting-edge findings, synthesize existing knowledge, and spark collaborative work across disciplines. Articles published in this issue will reach a broad audience of clinicians, researchers, and educators interested in mitochondrial biology and its impact on human health.
Categories and Accessibility
YJBM emphasizes open-access, evidence-based scholarship. Accepted manuscripts will contribute to a comprehensive resource platform for mitochondrial research, with potential for accompanying data sets and supplementary materials to support reproducibility and translational potential.
